Fecal microbiota transplantation enhanced the effect of chemoimmunotherapy by restoring intestinal microbiota in LLC tumor-bearing mice
There were no significant differences between HDC and SDC in their effects on the intestinal microbiota. FMT exhibited a beneficial impact on gut microbiota and improved the efficacy of chemoimmunotherapy, possibly associated with the increase of immune cells and the modulation of related cytokines and chemokines.
Authors
- Chunjian Qi (ORCID: https://orcid.org/0000-0001-9567-112X)
- Jingyan Yue
- Lanqun Qin
- Hua Jiang (ORCID: https://orcid.org/0000-0002-7871-4818)
- Xinmeng Wang (ORCID: https://orcid.org/0009-0007-1854-3205)
- Qian Geng (ORCID: https://orcid.org/0000-0003-2351-5042)
Institutions
- Changzhou No.2 People's Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- BMC Immunology
- Published
- 2025-04-08
- DOI
- https://doi.org/10.1186/s12865-025-00710-x
- Citations
- 5
- Primary Topic
- Clostridium difficile and Clostridium perfringens research
- Type
- article
- Field-Weighted Citation Impact
- 6.98
Funders
- Nanjing Medical University