Normative Modeling Reveals Age‐Atypical Cortical Thickness Differences Between Hepatic Steatosis and Fibrosis in Non‐Alcoholic Fatty Liver Disease
Distinct brain atrophy patterns were observed in NAFLD patients compared to the normal group, with more frequent temporal cortex outliers in both hepatic steatosis and fibrosis. Hepatic fibrosis showed slightly increased cortical thickness relative to steatosis.
Authors
- Kyu Sung Choi (ORCID: https://orcid.org/0000-0002-5175-3307)
- Joon Ho Moon (ORCID: https://orcid.org/0000-0003-1897-0905)
- Inpyeong Hwang (ORCID: https://orcid.org/0000-0002-1291-8973)
- Junhyeok Lee (ORCID: https://orcid.org/0000-0001-7489-5829)
- Jung Hyun Park (ORCID: https://orcid.org/0000-0003-4278-9778)
- Minchul Kim (ORCID: https://orcid.org/0000-0002-4614-1146)
- Munemasa Ryu
Institutions
- Seoul National University (KR)
- Seoul Metropolitan Government (KR)
- Seoul National University Hospital (KR)
- Seoul National University Bundang Hospital (KR)
- SNUH SMG-SNU Boramae Medical Center (KR)
- Kangbuk Samsung Hospital (KR)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- Brain and Behavior
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1002/brb3.70466
- Citations
- 1
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- National Research Foundation
- Sungkyunkwan University
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea
- Samsung