In vitro Antioxidant & Antidiabetic Activity of Indigofera prostrata

Numerous diseases, such as cancer, diabetes mellitus, aging, arthritis are linked to free radicals. Antioxidant therapy has become increasingly important in the management of several illnesses. Diabetes mellitus is an intricate metabolic ailment characterized by insistent hyperglycemia that interferes with protein, lipid and carbohydrate metabolism. Therefore, using a variety of conventional in vitro models, a modern investigation sought to investigate the antioxidant and antidiabetic properties of Indigofera prostrata. The methanol extracts of Indigofera prostrata were assessed in this endeavor for their ability to block radicals via the use of superoxide radical action, DPPH, lipid peroxidation assay, and the nitric oxide method. Numerous factors, including glucose diffusion, the inhibitory actions of alpha amylase, alpha glucosidase, and the ability of yeast cells to absorb glucose, were also used to measure the in vitro antidiabetic efficacy. When compared to conventional antioxidants, the revealed results of plant extracts demonstrated a higher capability for radical scavenging in relation to their antioxidant activity. Similarly, a variety of characteristics demonstrated that in vitro extracts of Indigofera prostrata had excellent antidiabetic action. In summary, Indigofera prostrata has strong anti-oxidant and antidiabetic qualities.

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Publication Details

Journal
Advances in Pharmacology and Pharmacy
Published
2025-04-08
DOI
https://doi.org/10.13189/app.2025.130305
Primary Topic
Natural Antidiabetic Agents Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

In vitro Antioxidant & Antidiabetic Activity of Indigofera prostrata

Kuchi Manjeera, Raja Sundararajan
Advances in Pharmacology and Pharmacy
Natural Antidiabetic Agents Studies
article

In vitro Antioxidant & Antidiabetic Activity of Indigofera prostrata

Kuchi Manjeera, Raja Sundararajan
article en

Abstract

Numerous diseases, such as cancer, diabetes mellitus, aging, arthritis are linked to free radicals. Antioxidant therapy has become increasingly important in the management of several illnesses. Diabetes mellitus is an intricate metabolic ailment characterized by insistent hyperglycemia that interferes with protein, lipid and carbohydrate metabolism. Therefore, using a variety of conventional in vitro models, a modern investigation sought to investigate the antioxidant and antidiabetic properties of Indigofera prostrata. The methanol extracts of Indigofera prostrata were assessed in this endeavor for their ability to block radicals via the use of superoxide radical action, DPPH, lipid peroxidation assay, and the nitric oxide method. Numerous factors, including glucose diffusion, the inhibitory actions of alpha amylase, alpha glucosidase, and the ability of yeast cells to absorb glucose, were also used to measure the in vitro antidiabetic efficacy. When compared to conventional antioxidants, the revealed results of plant extracts demonstrated a higher capability for radical scavenging in relation to their antioxidant activity. Similarly, a variety of characteristics demonstrated that in vitro extracts of Indigofera prostrata had excellent antidiabetic action. In summary, Indigofera prostrata has strong anti-oxidant and antidiabetic qualities.

Advances in Pharmacology and PharmacyVol. 13(3)
Gandhi Institute of Technology and Management
Zero hunger
Openalex Percentile: Top 90%
Natural Antidiabetic Agents Studies
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