Neutralization of <scp>IL</scp> ‐17 and <scp>CXCR1</scp> Protects Septic Arthritis by Regulating <scp>CXCL8</scp> ‐ <scp>CXCR1</scp> Pathway Along With Functional Activities in Neutrophils
We can conclude that IL-17 Ab in combination with gentamicin is potent in modulating neutrophil activities positively to cure sepsis, while CXCR1 Ab, through the CXCL8/CXCR1 pathway, regulates neutrophil functional activities by impacting different downstream signaling cascades.
Authors
- Sharmistha Ghosh (ORCID: https://orcid.org/0000-0002-4375-5652)
- Biswadev Bishayi (ORCID: https://orcid.org/0000-0001-8603-8621)
Institutions
- University of Calcutta (IN)
Publication Details
- Journal
- International Journal of Rheumatic Diseases
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1111/1756-185x.70144
- Primary Topic
- Immune Response and Inflammation
- Type
- article
- Field-Weighted Citation Impact
- 0.00