Exploring the molecular synergy of achyranthes bidentata and radix paeonia alba in antioxidant protection

Oxidative stress is a key contributor to various chronic diseases, and natural antioxidants have gained significant attention for their therapeutic potential. This study investigates the molecular synergy of Achyranthes bidentata (AB) and Radix Paeoniae Alba (RPA) in antioxidant protection. Through phytochemical analysis, in vitro antioxidant assays, and molecular docking, we explore their combined efficacy in scavenging reactive oxygen species (ROS) and modulating antioxidant enzyme activity. Our findings suggest that the bioactive compounds in AB and RPA exhibit a complementary mechanism in mitigating oxidative stress, highlighting their potential application in pharmacological formulations.

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Publication Details

Journal
International Journal of Pharmaceutical Research and Development
Published
2025-01-01
DOI
https://doi.org/10.33545/26646862.2025.v7.i1c.111
Primary Topic
Traditional Chinese Medicine Analysis
Type
article
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article

Exploring the molecular synergy of achyranthes bidentata and radix paeonia alba in antioxidant protection

Mukesh Kumar Meena, Priyanka Shivaji Kote, Komal P Bhonde, Pratima H Pokale et al.
International Journal of Pharmaceutical Research and Development
Traditional Chinese Medicine Analysis
article

Exploring the molecular synergy of achyranthes bidentata and radix paeonia alba in antioxidant protection

Mukesh Kumar Meena, Priyanka Shivaji Kote, Komal P Bhonde, Pratima H Pokale, Sanika P Kate
article en

Abstract

Oxidative stress is a key contributor to various chronic diseases, and natural antioxidants have gained significant attention for their therapeutic potential. This study investigates the molecular synergy of Achyranthes bidentata (AB) and Radix Paeoniae Alba (RPA) in antioxidant protection. Through phytochemical analysis, in vitro antioxidant assays, and molecular docking, we explore their combined efficacy in scavenging reactive oxygen species (ROS) and modulating antioxidant enzyme activity. Our findings suggest that the bioactive compounds in AB and RPA exhibit a complementary mechanism in mitigating oxidative stress, highlighting their potential application in pharmacological formulations.

International Journal of Pharmaceutical Research and DevelopmentVol. 7(1)
Openalex Percentile: Top 89%
Traditional Chinese Medicine Analysis
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