Revealing the Potential of Solamargine for Anti Metastasis and Angiogenesis Inhibition in Nasopharyngeal Carcinoma
SM inhibits NPC cell invasion and migration by regulating EMT, suppressing angiogenesis, and modulating key pathways. These findings highlight SM's potential as an anti-cancer agent for NPC and provide new insights into its mechanisms. Network pharmacology and GO-KEGG analysis further identify its therapeutic targets, offering valuable directions for future drug development.
Authors
- Jingjing Wu (ORCID: https://orcid.org/0000-0002-1736-5271)
- Xiaojuan Tang
- Yuan Lv (ORCID: https://orcid.org/0000-0003-1260-5800)
- Ling Han (ORCID: https://orcid.org/0000-0001-5812-555X)
- Changju Ma (ORCID: https://orcid.org/0000-0001-9055-7272)
- Yongheng He (ORCID: https://orcid.org/0000-0003-1314-3951)
- Yuan Ren (ORCID: https://orcid.org/0009-0009-8290-4663)
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Hunan Academy of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-04-01
- DOI
- https://doi.org/10.2147/jir.s485244
- Citations
- 1
- Primary Topic
- Synthesis and biological activity
- Type
- article
- Field-Weighted Citation Impact
- 0.94