Patterns of Polycystic Ovarian Syndrome, its Impact on Mental Well-Being, Health-Related Quality of Life, and Marital Satisfaction in Patients Presenting to the Outpatient Departments in Tertiary Care Hospitals of Peshawar

Objective: Assess the patterns of polycystic ovarian syndrome (PCOS), its effects on mental well-being, health-related quality of life, and marital satisfaction in women of childbearing age presenting to outpatient departments in tertiary care hospitals, in Peshawar. Methodology: A descriptive, cross-sectional study, was conducted on 384 patients after approval from the ethical committee of KMU, from 1st July to 31st December 2022. The participants completed a structured questionnaire independently or with medical personnel assistance. Multi-stage proportionate systematic random sampling technique was used. The SPSS version 25 was used for the statistical analyses. The effect of independent variables on dependent variables is ascertained by regression analysis, for categorical variables, frequencies, and percentages, mean and standard deviation (SD) for continuous variables, and a p-value of <0.05 used to explore associations between variables. The variables' associations and significance levels were evaluated using the t-test, multivariate logistic regression, and correlation analysis. Results: All married women between 15-44 years were selected, mean age was 27.25 years, 33.9%, illiterate, 46.6% were educated up to matric. Regarding BMI, using WHO criteria, 38.1% overweight, and 53.5% were obese. 94.5% had menstrual irregularities 85.3% had hyperandrogenism, 54.9% primary and 45.1% had secondary subfertility. The independent variables including subfertility, menstrual irregularities hyperandrogenism, and, BMI used to determine the impact on HADS, PCOSQOL, and ENRICH under three different models. Conclusion: Anxiety and depression are conditions that patients with PCOS should be assessed for since they impair quality of life and negatively affect marriages.