Unique Presentation of Glioblastoma With Acute Onset Symptomatology and Disease Recurrence

Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults. This devastating disease is well known for both its poor prognosis and rapid disease progression. Associated risk factors range from increasing age to certain predisposing genetic aberrations. Despite advances in surgical, therapeutic, and immunological therapies, there has been little improvement in the overall survival rate, and GBM remains an incurable disease. Here, we report the unique case of a 54-year-old female patient who was ultimately diagnosed with GBM after presenting with a very rapid onset of symptoms and discuss both the variability in the presentation of glioblastoma and the importance of monitoring for disease recurrence.