Hecate-FSHβ33-53C/S lytic peptide conjugate selectively kills targeted follicle stimulating hormone receptor (FSHR)-positive cancer cells
Hecate-FSHβ33-53C/S is highly effective in selectively targeting and killing FSHR-expressing cancer cells, with minimal side effects, suggesting its potential as a therapeutic option for cancers expressing FSH receptors.
Authors
- Sławomir Wołczyński (ORCID: https://orcid.org/0000-0002-7806-1394)
- Kamila Puławska (ORCID: https://orcid.org/0000-0002-9179-0444)
- Marcin Chruściel (ORCID: https://orcid.org/0000-0002-8757-9005)
- Joanna Stelmaszewska (ORCID: https://orcid.org/0000-0001-6612-8275)
- Nafis A. Rahman (ORCID: https://orcid.org/0000-0001-5257-870X)
- Milena Doroszko (ORCID: https://orcid.org/0000-0001-6844-9523)
- Adam J. Ziȩcik (ORCID: https://orcid.org/0000-0001-9163-9683)
- Donata Ponikwicka‐Tyszko (ORCID: https://orcid.org/0000-0003-1086-7460)
- Oliver J. Kreuzer
- Adolfo Rivero‐Müller (ORCID: https://orcid.org/0000-0002-9794-802X)
- Ilpo Huhtaniemi (ORCID: https://orcid.org/0000-0001-9092-7886)
- Xiangdong Li (ORCID: https://orcid.org/0000-0003-2261-2393)
Institutions
- Medical University of Lublin (PL)
- Medical University of Białystok (PL)
- University of Turku (FI)
- InLife Institute of Animal Reproduction and Food Research, Polish Academy of Sciences (PL)
- China Agricultural University (CN)
- Polish Academy of Sciences (PL)
Publication Details
- Journal
- Biomedicine & Pharmacotherapy
- Published
- 2025-04-08
- DOI
- https://doi.org/10.1016/j.biopha.2025.118022
- Citations
- 2
- Primary Topic
- Estrogen and related hormone effects
- Type
- article
- Field-Weighted Citation Impact
- 3.63
Funders
- Magnus Ehrnroothin Säätiö
- Uniwersytet Medyczny w Bialymstoku