Diagnostic Utility of Clusterin in Fine Needle Aspiration Biopsy and Core Biopsies of Hepatocellular Carcinoma

IHC for clusterin with enhanced canalicular pattern of expression revealed 68% sensitivity and 100% specificity for HCC, aiding its distinction from metastatic adenocarcinoma and benign hepatocytes in FNAB samples, thereby confirming its diagnostic utility.

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Publication Details

Journal
Diagnostic Cytopathology
Published
2025-04-08
DOI
https://doi.org/10.1002/dc.25473
Primary Topic
Clusterin in disease pathology
Type
article
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article

Diagnostic Utility of Clusterin in Fine Needle Aspiration Biopsy and Core Biopsies of Hepatocellular Carcinoma

Naveen Kalra, Madhumita Premkumar, Suvradeep Mitra, Reetu Kundu et al.
Diagnostic Cytopathology
Clusterin in disease pathology
article

Diagnostic Utility of Clusterin in Fine Needle Aspiration Biopsy and Core Biopsies of Hepatocellular Carcinoma

Naveen Kalra, Madhumita Premkumar, Suvradeep Mitra, Reetu Kundu, Radhika Srinivasan, Ajay Duseja, Bhawana Dhiman
article en

Abstract

IHC for clusterin with enhanced canalicular pattern of expression revealed 68% sensitivity and 100% specificity for HCC, aiding its distinction from metastatic adenocarcinoma and benign hepatocytes in FNAB samples, thereby confirming its diagnostic utility.

Diagnostic CytopathologyVol. 53(8)
Post Graduate Institute of Medical Education and Research (IN)
Good health and well-being
Openalex Percentile: Top 90%
Clusterin in disease pathology
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