Urinary [TIMP-2]•[IGFBP7], TIMP-2, IGFBP7, NGAL, and L-FABP for the prediction of acute kidney injury following cardiovascular surgery in Japanese patients
Our study demonstrated the good predictive performance of urine biomarkers, including [TIMP-2]•[IGFBP7], TIMP-2, IGFBP7, NGAL, and L-FABP, for any stage of cardiac surgery-associated AKI (CSA-AKI). The combination of TIMP-2 and IGFBP7 measured 2 h after postoperative ICU admission effectively predicted CSA-AKI, identifying patients at higher risk.
Authors
- Taro Horino (ORCID: https://orcid.org/0000-0003-0695-7981)
- Keisuke Yoshida
- Satoshi Inotani
- Yoshio Terada
- Takashi Kawano (ORCID: https://orcid.org/0000-0003-1332-7777)
- Hideki Iwata
- Yujiro Miura (ORCID: https://orcid.org/0000-0002-5763-6371)
- Yutaka Hatakeyama (ORCID: https://orcid.org/0000-0003-0004-5957)
- Keita Mitani
- Yuki Osakabe
Institutions
- Kōchi University (JP)
Publication Details
- Journal
- Clinical and Experimental Nephrology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.1007/s10157-025-02671-2
- Citations
- 2
- Primary Topic
- Acute Kidney Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 2.86