Huyang Yangkun Formula Enhances Ovarian Function and Delays Reproductive Aging by Influencing Hypothalamic GnRH/LH Pulse Release Through GAT-1/GABA/GABAAR2
HYF shows promise as a treatment for improving ovarian and reproductive neuroendocrine function in early reproductive aging, providing insights into its effects on hypothalamic GnRH/LH pulse release via the GAT-1/GABA/GABAAR2/GnRH pathway.
Authors
- Fangping Cheng
- Hongyan Yang (ORCID: https://orcid.org/0000-0003-4755-1857)
- Peng Yin (ORCID: https://orcid.org/0000-0002-2769-6357)
- Jian Liu (ORCID: https://orcid.org/0000-0001-9719-2923)
- Yang Li (ORCID: https://orcid.org/0000-0002-7677-9028)
- Guangning Nie
- Yuling Zhou
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Guangdong Provincial Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-04-01
- DOI
- https://doi.org/10.2147/dddt.s504610
- Primary Topic
- Menstrual Health and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00