Association between post COVID-19-related symptoms and quality of life two to three weeks after hospitalization: A cross-sectional study

The most frequently reported symptoms of the post-COVID-19 hospitalized patients are fatigue, dyspnea, anosmia, sleeping difficulties, chest pain, headache, cough, and mental health symptoms. Our aim was to identify common post-COVID-19 symptoms two to three weeks after the hospital discharge and their relationship with the quality of life. This cross-sectional study included 39 Post-Covid-19 patients who were discharged from the Clinic for Infectious Diseases at the University Clinical Center of Kosova UCCK. A list of symptoms of post-COVID-19 as defined by the Delphi consensus published by the WHO was recorded. Quality of life is measured using the EuroQol-5D-5L (EQ-5D-5L) instrument. Excessive tiredness (84.6%) and difficulty in breathing (64.1%) were the most common symptoms expressed by most participants. The EQ-5D-5L subscale -usual activity was correlated with excessive tiredness ( r = − 0.36; 95% CI: − 0.61 to − 0.05), dizziness ( r = − 0.34; 95% CI: − 0.59 to − 0.02), and depression and anxiety ( r = − 0.36; 95% CI: − 0.61 to − 0.05). The pain/discomfort subscale was correlated with chest pain ( r = − 0.45; 95% CI: − 0.67 to − 0.15), memory difficulties ( r = − 0.35; 95% CI: − 0.60 to − 0.04), palpitations ( r = − 0.38; 95% CI: − 0.62 to − 0.08), dizziness ( r = − 0.34; 95% CI: − 0.59 to − 0.03) and joint pain ( r = − 0.56; 95% CI: − 0.07 to − 0.30). Dizziness and joint pain were predictors of EQ-5D-5L index value, F (2, 36) = 10.73, p < 0.001. Excessive tiredness and difficulty in breathing were present in more than 50% of post-COVID-19′ patients 2–3 weeks after hospital discharge, while dizziness and joint pain could be predictors of diminished quality of life. Los síntomas mas frecuentes en pacientes hospitalizados tras sufrir COVID-19 incluyen fatiga, disnea, anosmia, dificultades para dormir, dolor torácico, cefalea, tos y síntomas relacionados con la salud mental. Nuestro objetivo fue identificar los síntomas comunes de relación con la calidad de vida. Este estudio transversal incluyó a 39 pacientes que habían sido hospitalizados por COVID-19 y dados de alta en la Clínica de Enfermedades Infecciosas del Centro Clínico Universitario de Kosovo (UCCK). Se registró una lista de síntomas de acuerdo con la definición del consenso Delphi publicada por la OMS. La calidad de visa se evaluó utilizando el instrumento EroQol-5D-5L (EQ-5D-5L). El cansancio excesivo (84,6%) y la dificultad para respirar (64,1%) fueron los síntomas más comunes reportados por los participantes. La subescala EQ-5D-5L -actividad habitual se correlacionó con cansancio excesivo ( r = − 0.36; IC del 95%: − 0.61 a − 0.05), mareos ( r = − 0.34; IC del 95%: − 0.59 a − 0.02) y depresión y ansiedad ( r = − 0.36; IC del 95%: − 0.61 a − 0.05). La subescala dolor/malestar se correlacionó con dolor en el pecho ( r = − 0.45; IC del 95%: − 0.67 a − 0.15), dificultades de memoria ( r = − 0.35; IC del 95%: − 0.60 a − 0.04), palpitaciones ( r = − 0.38; IC del 95%: − 0.62 a − 0.08), mareos ( r = − 0.34; IC del 95%: − 0.59 a − 0.03) y dolor en las articulaciones ( r = − 0.56; IC del 95%: − 0.075 a − 0.30). Además, los mareos y el dolor articular fueron predictores significativos del valor del índice EQ-5D-5L, F (2, 36) = 10.728, p < 0.001. El cansancio excesivo y la dificultad para respirar estuvieron presentes en más del 50% de los pacientes post COVID-19 2–3 semanas después del alta hospitalaria, mientras que los mareos y el dolor en las articulaciones podrían ser predictores de una calidad de vida disminuida.

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Journal
Medicina Clínica Práctica
Published
2025-04-08
DOI
https://doi.org/10.1016/j.mcpsp.2025.100501
Primary Topic
Long-Term Effects of COVID-19
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article
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article

Association between post COVID-19-related symptoms and quality of life two to three weeks after hospitalization: A cross-sectional study

Dafinë Ibrahimi Kaçuri, Arben Boshnjaku, Samire Beqaj, Arbnore Ibrahimaj Gashi et al.
Medicina Clínica Práctica
Long-Term Effects of COVID-19
article

Association between post COVID-19-related symptoms and quality of life two to three weeks after hospitalization: A cross-sectional study

Dafinë Ibrahimi Kaçuri, Arben Boshnjaku, Samire Beqaj, Arbnore Ibrahimaj Gashi, Merita Qorolli, Ardiana Murtezani
article en

Abstract

The most frequently reported symptoms of the post-COVID-19 hospitalized patients are fatigue, dyspnea, anosmia, sleeping difficulties, chest pain, headache, cough, and mental health symptoms. Our aim was to identify common post-COVID-19 symptoms two to three weeks after the hospital discharge and their relationship with the quality of life. This cross-sectional study included 39 Post-Covid-19 patients who were discharged from the Clinic for Infectious Diseases at the University Clinical Center of Kosova UCCK. A list of symptoms of post-COVID-19 as defined by the Delphi consensus published by the WHO was recorded. Quality of life is measured using the EuroQol-5D-5L (EQ-5D-5L) instrument. Excessive tiredness (84.6%) and difficulty in breathing (64.1%) were the most common symptoms expressed by most participants. The EQ-5D-5L subscale -usual activity was correlated with excessive tiredness ( r = − 0.36; 95% CI: − 0.61 to − 0.05), dizziness ( r = − 0.34; 95% CI: − 0.59 to − 0.02), and depression and anxiety ( r = − 0.36; 95% CI: − 0.61 to − 0.05). The pain/discomfort subscale was correlated with chest pain ( r = − 0.45; 95% CI: − 0.67 to − 0.15), memory difficulties ( r = − 0.35; 95% CI: − 0.60 to − 0.04), palpitations ( r = − 0.38; 95% CI: − 0.62 to − 0.08), dizziness ( r = − 0.34; 95% CI: − 0.59 to − 0.03) and joint pain ( r = − 0.56; 95% CI: − 0.07 to − 0.30). Dizziness and joint pain were predictors of EQ-5D-5L index value, F (2, 36) = 10.73, p < 0.001. Excessive tiredness and difficulty in breathing were present in more than 50% of post-COVID-19′ patients 2–3 weeks after hospital discharge, while dizziness and joint pain could be predictors of diminished quality of life. Los síntomas mas frecuentes en pacientes hospitalizados tras sufrir COVID-19 incluyen fatiga, disnea, anosmia, dificultades para dormir, dolor torácico, cefalea, tos y síntomas relacionados con la salud mental. Nuestro objetivo fue identificar los síntomas comunes de relación con la calidad de vida. Este estudio transversal incluyó a 39 pacientes que habían sido hospitalizados por COVID-19 y dados de alta en la Clínica de Enfermedades Infecciosas del Centro Clínico Universitario de Kosovo (UCCK). Se registró una lista de síntomas de acuerdo con la definición del consenso Delphi publicada por la OMS. La calidad de visa se evaluó utilizando el instrumento EroQol-5D-5L (EQ-5D-5L). El cansancio excesivo (84,6%) y la dificultad para respirar (64,1%) fueron los síntomas más comunes reportados por los participantes. La subescala EQ-5D-5L -actividad habitual se correlacionó con cansancio excesivo ( r = − 0.36; IC del 95%: − 0.61 a − 0.05), mareos ( r = − 0.34; IC del 95%: − 0.59 a − 0.02) y depresión y ansiedad ( r = − 0.36; IC del 95%: − 0.61 a − 0.05). La subescala dolor/malestar se correlacionó con dolor en el pecho ( r = − 0.45; IC del 95%: − 0.67 a − 0.15), dificultades de memoria ( r = − 0.35; IC del 95%: − 0.60 a − 0.04), palpitaciones ( r = − 0.38; IC del 95%: − 0.62 a − 0.08), mareos ( r = − 0.34; IC del 95%: − 0.59 a − 0.03) y dolor en las articulaciones ( r = − 0.56; IC del 95%: − 0.075 a − 0.30). Además, los mareos y el dolor articular fueron predictores significativos del valor del índice EQ-5D-5L, F (2, 36) = 10.728, p < 0.001. El cansancio excesivo y la dificultad para respirar estuvieron presentes en más del 50% de los pacientes post COVID-19 2–3 semanas después del alta hospitalaria, mientras que los mareos y el dolor en las articulaciones podrían ser predictores de una calidad de vida disminuida.

Medicina Clínica PrácticaVol. 8(3)
University Clinical Center of Kosovo (XK), University of Prishtina (XK)
Openalex Percentile: Top 88%
Long-Term Effects of COVID-19
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