Association between the lactate dehydrogenase-to-albumin ratio and 28-day mortality in septic patients with malignancies: analysis of the MIMIC-IV database
LDAR is a robust, independent prognostic biomarker for 28-day ICU mortality in septic patients with malignancies, outperforming traditional scoring systems. The identified threshold (log₂(LDAR) ≥ 6.940) may aid early risk stratification and clinical decision-making. Prospective studies are warranted to validate these findings and explore dynamic LDAR monitoring in diverse populations.
Authors
- Kangni Lin (ORCID: https://orcid.org/0000-0001-6589-2407)
- Wei Zhang (ORCID: https://orcid.org/0000-0001-9298-4497)
- Jinsen Weng
- Yongshi Shen
- Peng Zheng (ORCID: https://orcid.org/0000-0002-7743-9412)
- Yong Ye (ORCID: https://orcid.org/0000-0002-4681-1496)
- Liuxin Yang
Institutions
- Fujian Medical University (CN)
- Fujian Provincial Cancer Hospital (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-04-08
- DOI
- https://doi.org/10.1186/s12885-025-14013-2
- Citations
- 5
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 6.77