Real-world safety and efficacy of neoadjuvant docetaxel, cisplatin, and 5-fluorouracil therapy for locally advanced esophageal squamous cell carcinoma

Neoadjuvant DCF was effective and well-tolerated in real-world ESCC patients. Primary TRG grade 1a or pCR showed a favorable DFS/RFS, while positive ypN and GPS were independent risk factors for worse DFS/RFS.

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Publication Details

Journal
BMC Cancer
Published
2025-04-08
DOI
https://doi.org/10.1186/s12885-025-14011-4
Citations
1
Primary Topic
Esophageal Cancer Research and Treatment
Type
article
Field-Weighted Citation Impact
2.01
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article

Real-world safety and efficacy of neoadjuvant docetaxel, cisplatin, and 5-fluorouracil therapy for locally advanced esophageal squamous cell carcinoma

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1 citations
BMC Cancer
Esophageal Cancer Research and Treatment
2.01
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Real-world safety and efficacy of neoadjuvant docetaxel, cisplatin, and 5-fluorouracil therapy for locally advanced esophageal squamous cell carcinoma

Mikako Tamba, Shota Fukuoka, Akira Ooki, Jun Kanamori, Yu Imamura, Hiroki Osumi, Koichiro Yoshino, Takeru Wakatsuki, Eiji Shinozaki, Shohei Udagawa, Akihiko Okamura, Kensei Yamaguchi, Mariko Ogura, Masayuki Watanabe, Keisho Chin
article en
1 citations

Abstract

Neoadjuvant DCF was effective and well-tolerated in real-world ESCC patients. Primary TRG grade 1a or pCR showed a favorable DFS/RFS, while positive ypN and GPS were independent risk factors for worse DFS/RFS.

BMC CancerVol. 25(1)
Japanese Foundation For Cancer Research (JP)
Good health and well-being
Openalex Percentile: Top 17%
Esophageal Cancer Research and Treatment
2.01
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