Can the Mucosa Heal Histologically in Celiac Disease? What are the Indicators of Remission in Celiac Patients?

Diet compliance and remission rates of celiac patients increase over time. However, histologically, intraepithelial lymphocytosis almost never improves, and villous atrophy persists in most patients even if they comply with the diet. Although the asymptomatic nature of the patients, their autoantibody titers, and their dietary compliance are considered important indicators of remission, these parameters do not clearly reflect the histological status of the mucosa.

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Publication Details

Journal
The Turkish Journal of Gastroenterology
Published
2025-04-08
DOI
https://doi.org/10.5152/tjg.2025.24518
Primary Topic
Celiac Disease Research and Management
Type
article
Field-Weighted Citation Impact
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article

Can the Mucosa Heal Histologically in Celiac Disease? What are the Indicators of Remission in Celiac Patients?

Ahmet Yavuz, Berat Ebik, Ümit Karabulut, Ferhat Bacaksız et al.
The Turkish Journal of Gastroenterology
Celiac Disease Research and Management
article

Can the Mucosa Heal Histologically in Celiac Disease? What are the Indicators of Remission in Celiac Patients?

Ahmet Yavuz, Berat Ebik, Ümit Karabulut, Ferhat Bacaksız, Mustafa Zanyar Akkuzu, Muhsin Kaya
article en

Abstract

Diet compliance and remission rates of celiac patients increase over time. However, histologically, intraepithelial lymphocytosis almost never improves, and villous atrophy persists in most patients even if they comply with the diet. Although the asymptomatic nature of the patients, their autoantibody titers, and their dietary compliance are considered important indicators of remission, these parameters do not clearly reflect the histological status of the mucosa.

The Turkish Journal of GastroenterologyVol. 36(8)
Dicle University (TR), Sağlık Bilimleri Üniversitesi (TR), Diyarbakır Gazi Yaşargil Eğitim ve Araştırma Hastanesi (TR), University of Health Sciences Antigua (AG)
Zero hunger
Openalex Percentile: Top 89%
Celiac Disease Research and Management
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