Efficacy of Second-Line Treatments After Atezolizumab and Bevacizumab in Advanced Hepatocellular Carcinoma and Related Prognostic Factors: A Multicenter Study by the Turkish Oncology Group (TOG)
Although second-line therapies after Atez/Bev show different degrees of efficacy, survival rates are consistent with the literature. Extrahepatic spread, AFP level, and PNI level are the main prognostic factors. In light of this information, personalized treatment strategies may improve outcomes for this challenging patient group.
Authors
- Şendağ Yaslıkaya (ORCID: https://orcid.org/0000-0001-5264-8405)
- Ahmet Bılıcı (ORCID: https://orcid.org/0000-0002-0443-6966)
- Ahmet Bilgehan Şahin (ORCID: https://orcid.org/0000-0002-7846-0870)
- Özkan Alan (ORCID: https://orcid.org/0000-0002-6635-2012)
- Arif Akyıldız (ORCID: https://orcid.org/0000-0002-4452-2076)
- Osman Köstek (ORCID: https://orcid.org/0000-0002-1901-5603)
- Nargız Majidova (ORCID: https://orcid.org/0000-0002-2575-5819)
- İsmail Bayrakçı (ORCID: https://orcid.org/0000-0002-5785-8273)
- Damla Günenç (ORCID: https://orcid.org/0000-0002-7592-2021)
- Taha Koray Şahin (ORCID: https://orcid.org/0000-0002-3590-0426)
- Ali Kaan Güren (ORCID: https://orcid.org/0000-0002-3562-5006)
- Suayip Yalcın
- Teoman Şakalar (ORCID: https://orcid.org/0000-0003-2749-9414)
- Musa Barış Aykan (ORCID: https://orcid.org/0000-0001-7538-9119)
- Murat Araz (ORCID: https://orcid.org/0000-0002-4632-9501)
- Hüseyin Atacan
- Fatih Selçukbırıcık (ORCID: https://orcid.org/0000-0002-1273-1674)
- Elif Şahin (ORCID: https://orcid.org/0000-0002-1976-3951)
- Ahmet Ünsal (ORCID: https://orcid.org/0000-0001-8625-0761)
- İsmail Oğuz Kara (ORCID: https://orcid.org/0000-0003-4963-2028)
- Ceren Mordağ Çiçek (ORCID: https://orcid.org/0000-0002-9140-1453)
- Duygu Ercan Uzundal
- Buket Hamitoğlu (ORCID: https://orcid.org/0000-0003-2002-3931)
- Bülent Erdoğan (ORCID: https://orcid.org/0000-0002-2158-3490)
- Deniz Can Güven (ORCID: https://orcid.org/0000-0002-6924-9467)
- Olçun Ümit Ünal (ORCID: https://orcid.org/0000-0001-7698-3574)
- Esra Özen Engin (ORCID: https://orcid.org/0000-0002-5225-1456)
- Sinem Akbaş (ORCID: https://orcid.org/0000-0002-7197-211X)
- Nurullah İlhan
- Nadiye Sever
- Nuriye Özdemir
- Maral Martin Mıldanoğlu (ORCID: https://orcid.org/0000-0002-4587-0726)
- Alper Coşkun (ORCID: https://orcid.org/0000-0003-2444-6587)
- Ufuk Camanlı (ORCID: https://orcid.org/0000-0003-4494-9309)
Institutions
- Sakarya University (TR)
- Trakya University (TR)
- Bursa Uludağ Üni̇versi̇tesi̇ (TR)
- Koç University (TR)
- Gümüşhane University (TR)
- Dokuz Eylül University (TR)
- Istanbul Medipol University (TR)
- Ege University (TR)
- Gülhane Askerî Tıp Akademisi (TR)
- Necmettin Erbakan University (TR)
- Hacettepe University Hospital (TR)
- Education Training And Research (US)
- Izmir Tepecik Eğitim ve Araştırma Hastanesi (TR)
- Izmir Bozyaka Eğitim ve Araştırma Hastanesi (TR)
- Maltepe University (TR)
- Kahramanmaraş Sütçü İmam University (TR)
- Pamukkale University (TR)
- Kocaeli Üniversitesi (TR)
- Cukurova University (TR)
- Hacettepe University (TR)
- Marmara University (TR)
- Gazi University (TR)
Publication Details
- Journal
- The Turkish Journal of Gastroenterology
- Published
- 2025-04-07
- DOI
- https://doi.org/10.5152/tjg.2025.24784
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00