Targeting All Multiple Magnetic Resonance Imaging Prostate Lesions Does Not Enhance Cancer Detection: Insights from the YAU Prostate Cancer Group
We studied whether targeting multiple suspicious areas on prostate magnetic resonance imaging increases cancer detection. We found that patients with multiple lesions had a lower risk of prostate cancer than those with a single lesion. Targeting the largest suspicious area along with sampling the entire prostate led to the detection of most cancer cases, with little added benefit from targeting the other smaller areas.
Authors
- Giuseppe Ottone Cirulli
- Paweł Rajwa (ORCID: https://orcid.org/0000-0003-4073-6584)
- Fabrizio Moro (ORCID: https://orcid.org/0000-0001-8850-9239)
- Alessandro Marquis (ORCID: https://orcid.org/0000-0002-6808-148X)
- Roderick van den Bergh
- Claudia Kesch (ORCID: https://orcid.org/0000-0002-2656-2664)
- Filippo Carletti (ORCID: https://orcid.org/0009-0008-1848-584X)
- Francesco Barletta (ORCID: https://orcid.org/0000-0003-3585-3217)
- Junlong Zhuang (ORCID: https://orcid.org/0000-0001-5150-3669)
- Tamás Fazekas (ORCID: https://orcid.org/0000-0003-0068-4089)
- Alberto Briganti (ORCID: https://orcid.org/0000-0002-2178-0494)
- Alberto Martini (ORCID: https://orcid.org/0000-0003-1272-7154)
- Maria Apfelbeck (ORCID: https://orcid.org/0000-0002-9223-9291)
- Hongqian Guo
- Giacomo Novara (ORCID: https://orcid.org/0000-0003-4693-5058)
- Massimo Valério (ORCID: https://orcid.org/0000-0002-1059-2340)
- Peter Ka‐Fung Chiu (ORCID: https://orcid.org/0000-0002-1499-8372)
- Giorgio Gandaglia
- Alexander Kretschmer (ORCID: https://orcid.org/0000-0002-6511-4354)
- Giancarlo Marra
- Riccardo Leni (ORCID: https://orcid.org/0000-0003-0779-0984)
- Jonathan Olivier (ORCID: https://orcid.org/0000-0002-5409-2911)
- Fabio Zattoni (ORCID: https://orcid.org/0000-0002-4178-373X)
- Guillaume Ploussard (ORCID: https://orcid.org/0000-0003-3799-4988)
- Paolo Gontero
- Francesco Giganti
- Veeru Kasivisvanathan
Institutions
- Semmelweis University (HU)
- University of Geneva (CH)
- University College London Hospitals NHS Foundation Trust (GB)
- University of Padua (IT)
- Chinese University of Hong Kong (HK)
- Université de Lille (FR)
- LMU Klinikum (DE)
- Fondazione Ricerca Molinette (IT)
- St. Antonius Ziekenhuis (NL)
- University Hospital of Geneva (CH)
- Nanjing Drum Tower Hospital (CN)
- Essen University Hospital (DE)
- IRCCS Ospedale San Raffaele (IT)
- Postgraduate School of Molecular Medicine (PL)
- University College London (GB)
- University of Turin (IT)
- University of Cincinnati (US)
- Medical University of Vienna (AT)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- European Urology Open Science
- Published
- 2025-04-08
- DOI
- https://doi.org/10.1016/j.euros.2025.03.008
- Citations
- 3
- Primary Topic
- Prostate Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.56