The Role of Pulmonary Genetic Variations in the Pathogenesis of Pediatric Postinfectious Bronchiolitis Obliterans

Heterozygous variations associated with pulmonary diseases, including the <i>MUC5B</i> and <i>DNAH</i> genes, and CSF2RB, were identified in most patients diagnosed with PIBO, which may have clinical significance. These data are valuable in hypothesis formation that may lead to the evaluation of these three genes in the pathogenesis of PIBO in children.

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Publication Details

Journal
Thoracic research and practice
Published
2025-04-08
DOI
https://doi.org/10.4274/thoracrespract.2025.2024-11-1
Primary Topic
Transplantation: Methods and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

The Role of Pulmonary Genetic Variations in the Pathogenesis of Pediatric Postinfectious Bronchiolitis Obliterans

Merve Öçalan, Hasan Yüksel, Sedef Narin Tongal, Gülsüm Kayhan et al.
Thoracic research and practice
Transplantation: Methods and Outcomes
article

The Role of Pulmonary Genetic Variations in the Pathogenesis of Pediatric Postinfectious Bronchiolitis Obliterans

Merve Öçalan, Hasan Yüksel, Sedef Narin Tongal, Gülsüm Kayhan, Özge Yılmaz
article en

Abstract

Heterozygous variations associated with pulmonary diseases, including the <i>MUC5B</i> and <i>DNAH</i> genes, and CSF2RB, were identified in most patients diagnosed with PIBO, which may have clinical significance. These data are valuable in hypothesis formation that may lead to the evaluation of these three genes in the pathogenesis of PIBO in children.

Thoracic research and practiceVol. 26(4)
Manisa Celal Bayar University (TR), Gazi University (TR)
Zero hunger
Openalex Percentile: Top 88%
Transplantation: Methods and Outcomes
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