Treat to Target Suggestions in Gout - a Different View

Despite significant progress has been made with understanding and treating gout since the mid-20th century, the disease remains challenging to manage to for a considerable percentage of patients. Treatment success often requires several years to achieve. We aim to demonstrate that successful gout treatment can be accomplished much earlier by use of moderate doses of currently available medications. Compared to pegloticase, regimens described here will be similarly effective in a minority of patients and only slightly less effective in a high percentage of patients. By employing such treatment strategies, gout can be cured within one to two years in most patients, with treatment durations exceeding two years being rare. Given the long-term consequences of chronic subclinical inflammation associated with gout, we conclude that the disease can be cured very much earlier than suggested by current guidelines.