Bacterial infection in patients with juvenile systemic lupus erythematosus and fever
Bacterial infection was detected in 17% of JSLE patients with fever. Procalcitonin > 0.9 ng/mL is a critical marker for identifying bacterial infection. NLR, PLR, ESR/CRP ratio, LC4R, and ferritin require further investigation to establish definitive cut-off values for differentiating bacterial infections from other infections or disease activity. Individual patient evaluation remains the recommended approach for diagnosis.
Authors
- Juan Pablo Rojas Hernández (ORCID: https://orcid.org/0000-0003-4704-2171)
- José Fernando Gómez Urrego (ORCID: https://orcid.org/0000-0003-4708-7759)
- Nathalie Yepes Madrid (ORCID: https://orcid.org/0000-0002-2740-2072)
- Luis Fernando Mejía-Rivera
- Robinson Pacheco (ORCID: https://orcid.org/0000-0003-2525-9935)
- Mónica Alexandra Gil-Artunduaga
- María Del Pilar Gómez-Mora
Institutions
- Boston Medical Group (Colombia) (CO)
- Infectious Disease Consultants (US)
- ProPacífico (CO)
- UniBrasil Centro Universitário (BR)
- Center for Rheumatology (US)
- Hospital Universitario Infantil San José (CO)
- Universidad Libre de Colombia (CO)
- Universidad del Valle (CO)
Publication Details
- Journal
- Pediatric Rheumatology
- Published
- 2025-04-08
- DOI
- https://doi.org/10.1186/s12969-025-01088-1
- Citations
- 1
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 1.67