Hirsutine attenuated oxidative stress and autophagy in diabetic kidney disease through Keap1/Nrf2 pathway
Hirsutine exhibited renoprotective effects in DKD by modulating the Keap1/Nrf2 pathway, mitigating oxidative stress and promoting autophagy, making it a promising candidate for treatment.
Authors
- Miao Tan (ORCID: https://orcid.org/0000-0003-2400-1828)
- Jinchuan Tan (ORCID: https://orcid.org/0000-0002-7406-5400)
- Bing Yang (ORCID: https://orcid.org/0000-0001-6183-8163)
- Yao Zhang (ORCID: https://orcid.org/0000-0002-8180-7361)
Institutions
- First Affiliated Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- Journal of Pharmacological Sciences
- Published
- 2025-04-08
- DOI
- https://doi.org/10.1016/j.jphs.2025.04.002
- Citations
- 4
- Primary Topic
- Genomics, phytochemicals, and oxidative stress
- Type
- article
- Field-Weighted Citation Impact
- 3.22