Human papillomavirus genotype distribution and its correlation with intraepithelial neoplasia, vaccination, and ethnicity

HPV non-16/18 genotypes are more prevalent than HPV 16/18, even in women with high-grade lesions with a greater shift towards non-16/18 genotypes in non-white and in vaccinated women. The study suggests the need for extended HPV genotyping and vaccines targeting a broader range of HPV types to include HPV non-16/18 to improve prevention, particularly in certain ethnic groups.

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Publication Details

Journal
Journal of the American Society of Cytopathology
Published
2025-04-08
DOI
https://doi.org/10.1016/j.jasc.2025.03.006
Primary Topic
Cervical Cancer and HPV Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Human papillomavirus genotype distribution and its correlation with intraepithelial neoplasia, vaccination, and ethnicity

Uma Krishnamurti, Tong Sun, Rita Abi‐Raad
Journal of the American Society of Cytopathology
Cervical Cancer and HPV Research
article

Human papillomavirus genotype distribution and its correlation with intraepithelial neoplasia, vaccination, and ethnicity

Uma Krishnamurti, Tong Sun, Rita Abi‐Raad
article en

Abstract

HPV non-16/18 genotypes are more prevalent than HPV 16/18, even in women with high-grade lesions with a greater shift towards non-16/18 genotypes in non-white and in vaccinated women. The study suggests the need for extended HPV genotyping and vaccines targeting a broader range of HPV types to include HPV non-16/18 to improve prevention, particularly in certain ethnic groups.

Journal of the American Society of CytopathologyVol. 14(4)
Yale University (US)
Openalex Percentile: Top 89%
Cervical Cancer and HPV Research
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