Structural brain pattern abnormalities in tinnitus with and without hearing loss
Our findings revealed that tinnitus-related structural brain patterns involve regions such as the middle frontal gyrus, supplementary motor area (SMA), and anterior cingulate cortex (ACC), with these changes negatively correlating with tinnitus distress, suggesting adaptive mechanisms in tinnitus perception. Moreover, the structural brain pattern involving the insula, putamen, and superior temporal gyrus appears to be primarily driven by hearing loss. These findings support audiometric-based subgrouping in tinnitus management.
Authors
- Yu‐Feng Zang (ORCID: https://orcid.org/0000-0003-1833-8010)
- Chengchao Shi
- Eugene Jennifer Jin (ORCID: https://orcid.org/0000-0002-7714-9634)
- Yuan Li (ORCID: https://orcid.org/0000-0001-9809-9894)
- Jiaying Wang (ORCID: https://orcid.org/0000-0002-4837-6686)
- Qin Li (ORCID: https://orcid.org/0000-0001-9210-8948)
- Zheng Qin Yin (ORCID: https://orcid.org/0000-0002-4253-7485)
- Qiu Ge
- J H Ni
Institutions
- Affiliated Hospital of Hangzhou Normal University (CN)
Publication Details
- Journal
- Hearing Research
- Published
- 2025-04-08
- DOI
- https://doi.org/10.1016/j.heares.2025.109274
- Citations
- 1
- Primary Topic
- Hearing, Cochlea, Tinnitus, Genetics
- Type
- article
- Field-Weighted Citation Impact
- 1.46