Association of total and bioactive serum sclerostin levels with bone metabolism in type 2 diabetes mellitus
We demonstrate a significant positive association of bioactive serum sclerostin with BMD at all measured sites in patients with T2DM, which may support its utility in the assessment of bone fragility in this population.
Authors
- Sandra Baumann
- Janina Vavanikunnel (ORCID: https://orcid.org/0000-0001-5840-7100)
- Christian Meier (ORCID: https://orcid.org/0000-0002-0619-821X)
- Christoph Henzen (ORCID: https://orcid.org/0000-0002-7075-8947)
- Cyril Traechslin
- Marius Kraenzlin
- Lilian Sewing (ORCID: https://orcid.org/0000-0001-5321-844X)
- Leticia Grize (ORCID: https://orcid.org/0000-0001-5096-5693)
Institutions
- Swiss Tropical and Public Health Institute (CH)
- University of Lucerne (CH)
- University Hospital of Basel (CH)
- Freiwillige Akademische Gesellschaft (CH)
- Regionalspital Emmental (CH)
- Luzerner Kantonsspital (CH)
- Kantonsschule Olten (CH)
Publication Details
- Journal
- Journal of Clinical & Translational Endocrinology
- Published
- 2025-04-08
- DOI
- https://doi.org/10.1016/j.jcte.2025.100393
- Citations
- 2
- Primary Topic
- Bone health and osteoporosis research
- Type
- article
- Field-Weighted Citation Impact
- 3.44
Funders
- Roche
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Schweizerischen Gesellschaft für Endokrinologie und Diabetologie