Histological Characteristics of the Filum Terminale in Occult Tethered Cord Syndrome and Filum Terminale Lipoma
The observed decrease in collagen type I and elastic fibers in OTCS suggests compromised filum terminale elasticity, potentially contributing to pathological tethering. In FTL, adipose infiltration is the primary factor driving spinal cord traction, although some cases also showed reduced elastic fiber integrity. These findings emphasize the importance of further research into the relationship between histopathological changes and clinical presentations. Better understanding of this correlation is crucial for developing standardized management strategies.
Authors
- Masataka Hayashi (ORCID: https://orcid.org/0000-0002-1823-0205)
- Fumitaka Sato (ORCID: https://orcid.org/0000-0002-0828-5720)
- Tomoya Arakawa
- Yoshiro Otsuki (ORCID: https://orcid.org/0000-0002-0568-3811)
- Hirokazu Nakatogawa (ORCID: https://orcid.org/0000-0002-4241-3028)
- Chikanori Inenaga
- Tomohiro Nakamura (ORCID: https://orcid.org/0000-0003-0051-2033)
Institutions
- Seirei Hamamatsu General Hospital (JP)
Publication Details
- Journal
- World Neurosurgery
- Published
- 2025-04-09
- DOI
- https://doi.org/10.1016/j.wneu.2025.123962
- Citations
- 2
- Primary Topic
- Testicular diseases and treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.01