Histological Characteristics of the Filum Terminale in Occult Tethered Cord Syndrome and Filum Terminale Lipoma

The observed decrease in collagen type I and elastic fibers in OTCS suggests compromised filum terminale elasticity, potentially contributing to pathological tethering. In FTL, adipose infiltration is the primary factor driving spinal cord traction, although some cases also showed reduced elastic fiber integrity. These findings emphasize the importance of further research into the relationship between histopathological changes and clinical presentations. Better understanding of this correlation is crucial for developing standardized management strategies.

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Publication Details

Journal
World Neurosurgery
Published
2025-04-09
DOI
https://doi.org/10.1016/j.wneu.2025.123962
Citations
2
Primary Topic
Testicular diseases and treatments
Type
article
Field-Weighted Citation Impact
4.01
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article

Histological Characteristics of the Filum Terminale in Occult Tethered Cord Syndrome and Filum Terminale Lipoma

Masataka Hayashi, Fumitaka Sato, Tomoya Arakawa, Yoshiro Otsuki et al.
2 citations
World Neurosurgery
Testicular diseases and treatments
4.01
article

Histological Characteristics of the Filum Terminale in Occult Tethered Cord Syndrome and Filum Terminale Lipoma

Masataka Hayashi, Fumitaka Sato, Tomoya Arakawa, Yoshiro Otsuki, Hirokazu Nakatogawa, Chikanori Inenaga, Tomohiro Nakamura
article en
2 citations

Abstract

The observed decrease in collagen type I and elastic fibers in OTCS suggests compromised filum terminale elasticity, potentially contributing to pathological tethering. In FTL, adipose infiltration is the primary factor driving spinal cord traction, although some cases also showed reduced elastic fiber integrity. These findings emphasize the importance of further research into the relationship between histopathological changes and clinical presentations. Better understanding of this correlation is crucial for developing standardized management strategies.

World NeurosurgeryVol. 198
Seirei Hamamatsu General Hospital (JP)
Life below water
Openalex Percentile: Top 8%
Testicular diseases and treatments
4.01
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