Particulate matter exposure induces pulmonary TH2 responses and oxidative stress-mediated NRF2 activation in mice
These findings highlight how PM exposure disrupts immune balance and exacerbates conditions like asthma and chronic obstructive pulmonary disease by promoting T<sub>H</sub>2-driven inflammation through NRF2 activation.
Authors
- Ji Hyeon Ryu (ORCID: https://orcid.org/0000-0003-0342-3108)
- Changwan Hong (ORCID: https://orcid.org/0000-0003-2567-2973)
- Woo Seok Kim (ORCID: https://orcid.org/0000-0001-6796-4312)
- Jong‐Eun Park (ORCID: https://orcid.org/0000-0003-0718-3463)
- Yuna Jo (ORCID: https://orcid.org/0000-0002-5756-4873)
- Yong‐Il Shin (ORCID: https://orcid.org/0000-0001-7894-0930)
- Jun Hong Park (ORCID: https://orcid.org/0000-0001-8905-4125)
- Bo-Young Kim (ORCID: https://orcid.org/0009-0007-3327-2730)
- Ji‐Su Park (ORCID: https://orcid.org/0000-0001-7113-4792)
- Ju A Shim
- So Min Lee (ORCID: https://orcid.org/0000-0002-3839-6480)
Institutions
- Korea Advanced Institute of Science and Technology (KR)
- Pusan National University Yangsan Hospital (KR)
- Pusan National University (KR)
- Jeonbuk National University (KR)
Publication Details
- Journal
- Redox Biology
- Published
- 2025-04-08
- DOI
- https://doi.org/10.1016/j.redox.2025.103632
- Citations
- 7
- Primary Topic
- Air Quality and Health Impacts
- Type
- article
- Field-Weighted Citation Impact
- 8.40