Federated epidemic surveillance

Epidemic surveillance is a challenging task, especially when crucial data is fragmented across institutions and data custodians are unable or unwilling to share it. This study aims to explore the feasibility of a simple federated surveillance approach. We conduct hypothesis tests on count data behind each custodian's firewall and then combine p-values from these tests using techniques from meta-analysis. We propose a hypothesis testing framework to identify surges in epidemic-related data streams and conduct experiments on real and semi-synthetic data to assess the power of different p-value combination methods to detect surges without needing to combine or share the underlying counts. Our findings show that relatively simple combination methods achieve a high degree of fidelity and suggest that infectious disease outbreaks can be detected without needing to share or even aggregate data across institutions.

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Publication Details

Journal
PLoS Computational Biology
Published
2025-04-08
DOI
https://doi.org/10.1371/journal.pcbi.1012907
Citations
2
Primary Topic
Data-Driven Disease Surveillance
Type
article
Field-Weighted Citation Impact
2.71
Controls
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article

Federated epidemic surveillance

Ruiqi Lyu, Roni Rosenfeld, Bryan Wilder
2 citations
PLoS Computational Biology
Data-Driven Disease Surveillance
2.71
article

Federated epidemic surveillance

Ruiqi Lyu, Roni Rosenfeld, Bryan Wilder
article en
2 citations

Abstract

Epidemic surveillance is a challenging task, especially when crucial data is fragmented across institutions and data custodians are unable or unwilling to share it. This study aims to explore the feasibility of a simple federated surveillance approach. We conduct hypothesis tests on count data behind each custodian's firewall and then combine p-values from these tests using techniques from meta-analysis. We propose a hypothesis testing framework to identify surges in epidemic-related data streams and conduct experiments on real and semi-synthetic data to assess the power of different p-value combination methods to detect surges without needing to combine or share the underlying counts. Our findings show that relatively simple combination methods achieve a high degree of fidelity and suggest that infectious disease outbreaks can be detected without needing to share or even aggregate data across institutions.

PLoS Computational BiologyVol. 21(4)
Carnegie Mellon University (US)
Good health and well-being
Openalex Percentile: Top 11%
Data-Driven Disease Surveillance
2.71
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