Federated epidemic surveillance
Epidemic surveillance is a challenging task, especially when crucial data is fragmented across institutions and data custodians are unable or unwilling to share it. This study aims to explore the feasibility of a simple federated surveillance approach. We conduct hypothesis tests on count data behind each custodian's firewall and then combine p-values from these tests using techniques from meta-analysis. We propose a hypothesis testing framework to identify surges in epidemic-related data streams and conduct experiments on real and semi-synthetic data to assess the power of different p-value combination methods to detect surges without needing to combine or share the underlying counts. Our findings show that relatively simple combination methods achieve a high degree of fidelity and suggest that infectious disease outbreaks can be detected without needing to share or even aggregate data across institutions.
Authors
- Ruiqi Lyu (ORCID: https://orcid.org/0000-0001-7062-1476)
- Roni Rosenfeld (ORCID: https://orcid.org/0000-0002-3274-5862)
- Bryan Wilder (ORCID: https://orcid.org/0000-0002-9410-020X)
Institutions
- Carnegie Mellon University (US)
Publication Details
- Journal
- PLoS Computational Biology
- Published
- 2025-04-08
- DOI
- https://doi.org/10.1371/journal.pcbi.1012907
- Citations
- 2
- Primary Topic
- Data-Driven Disease Surveillance
- Type
- article
- Field-Weighted Citation Impact
- 2.71