Line-field confocal optical coherence tomography-controlled cryotherapy for extramammary Paget disease: a case report
A 73-year-old man presented with recurrent primary perianal extramammary Paget disease. The patient declined both surgery and topical imiquimod and preferred cryotherapy from the other available noninvasive therapeutic options. At the 1-month follow-up visit, a complete response to treatment was suspected both on clinical and dermoscopic examination. This response was confirmed by line-field confocal optical coherence tomography (LC-OCT), which demonstrated the efficacy of the treatment by the absence of Paget cells. For patients seeking less-invasive treatment options, LC-OCT-controlled cryotherapy not only reduces invasiveness but also allows for accurate real-time monitoring.
Authors
- Linda Tognetti (ORCID: https://orcid.org/0000-0002-6691-4310)
- Mariano Suppa (ORCID: https://orcid.org/0000-0002-9266-0342)
- Gerardo Palmisano (ORCID: https://orcid.org/0009-0000-9681-1681)
- G. Diet (ORCID: https://orcid.org/0009-0000-2934-7049)
- Josep Malvehy (ORCID: https://orcid.org/0000-0002-6998-914X)
- Javiera Pérez‐Ánker (ORCID: https://orcid.org/0000-0002-6959-7250)
- Élisa Cinotti (ORCID: https://orcid.org/0000-0002-4009-0659)
- V. del Mármol (ORCID: https://orcid.org/0000-0002-4359-0667)
- Susana Puig (ORCID: https://orcid.org/0000-0003-1337-9745)
- Carmen Orte Cano (ORCID: https://orcid.org/0000-0002-1570-7856)
- Ketty Peris (ORCID: https://orcid.org/0000-0002-5237-0463)
- Pietro Rubegni (ORCID: https://orcid.org/0000-0002-4128-3145)
- Jean‐Luc Perrot
Institutions
- University of Siena (IT)
- Università Cattolica del Sacro Cuore (IT)
- Université Libre de Bruxelles (BE)
- Instituto de Salud Carlos III (ES)
- Institut Jules Bordet (BE)
- Erasmus Hospital (BE)
- Agostino Gemelli University Polyclinic (IT)
- Centro de Investigación Biomédica en Red (ES)
- Société Française de Cardiologie (FR)
- University of the Sacred Heart (JP)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Centre Hospitalier Universitaire de Saint-Étienne (FR)
- Universitat de Barcelona (ES)
Publication Details
- Journal
- Clinical and Experimental Dermatology
- Published
- 2025-04-08
- DOI
- https://doi.org/10.1093/ced/llaf161
- Citations
- 1
- Primary Topic
- Cancer and Skin Lesions
- Type
- article
- Field-Weighted Citation Impact
- 2.00