Bilateral malignant struma ovarii with concurrent thyroid carcinoma

Malignant struma ovarii (MSO) is a rare ovarian tumour. The co-occurrence of MSO and thyroid carcinoma is even rarer. There is no established treatment for these patients. We report a postmenopausal woman in her 60s who presented with left hip pain, increased urinary frequency and fatigue. Imaging showed a left adnexal cystic lesion 8.8 cm in diameter and an incidental 12×8 mm right ovarian cyst. She underwent total laparoscopic hysterectomy and bilateral salpingo-oophorectomy, and findings were significant for bilateral stage IA MSO. The metastatic workup showed concurrent papillary thyroid carcinoma. She underwent total thyroidectomy with neck dissection and radioactive iodine (RAI) adjuvant therapy. While thyroid carcinoma management is more standardised, a literature review yielded a wide range of MSO treatments. Recent literature favours conservative management with unilateral salpingo-oophorectomy. RAI therapy in these cases is controversial. We will discuss the literature findings on the optimal treatment of MSO with concurrent thyroid cancer.

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Publication Details

Journal
BMJ Case Reports
Published
2025-04-01
DOI
https://doi.org/10.1136/bcr-2024-263514
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
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article

Bilateral malignant struma ovarii with concurrent thyroid carcinoma

Karim ElSahwi, Pritinder K. Thind, Danielle Lann, Gwendolyn Glatz
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BMJ Case Reports
Ovarian cancer diagnosis and treatment
article

Bilateral malignant struma ovarii with concurrent thyroid carcinoma

Karim ElSahwi, Pritinder K. Thind, Danielle Lann, Gwendolyn Glatz
article en

Abstract

Malignant struma ovarii (MSO) is a rare ovarian tumour. The co-occurrence of MSO and thyroid carcinoma is even rarer. There is no established treatment for these patients. We report a postmenopausal woman in her 60s who presented with left hip pain, increased urinary frequency and fatigue. Imaging showed a left adnexal cystic lesion 8.8 cm in diameter and an incidental 12×8 mm right ovarian cyst. She underwent total laparoscopic hysterectomy and bilateral salpingo-oophorectomy, and findings were significant for bilateral stage IA MSO. The metastatic workup showed concurrent papillary thyroid carcinoma. She underwent total thyroidectomy with neck dissection and radioactive iodine (RAI) adjuvant therapy. While thyroid carcinoma management is more standardised, a literature review yielded a wide range of MSO treatments. Recent literature favours conservative management with unilateral salpingo-oophorectomy. RAI therapy in these cases is controversial. We will discuss the literature findings on the optimal treatment of MSO with concurrent thyroid cancer.

BMJ Case ReportsVol. 18(4)
Jersey Shore University Medical Center (US)
Good health and well-being
Openalex Percentile: Top 90%
Ovarian cancer diagnosis and treatment
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