Causal relationship between breast cancer and acute myeloid leukemia based on two-sample bidirectional Mendelian randomization and transcriptome overlap analysis
MR analyses indicated a causal relationship between breast cancer and AML. Additionally, transcriptome analysis offered a theoretical basis for understanding the potential mechanisms and therapeutic targets of AML in breast cancer patients.
Authors
- Chong Huang (ORCID: https://orcid.org/0000-0002-0392-9398)
- Xinyi Bai (ORCID: https://orcid.org/0009-0002-7594-4404)
- Xinan Pan (ORCID: https://orcid.org/0000-0001-8539-9345)
- Fei Li (ORCID: https://orcid.org/0000-0002-0532-9054)
Institutions
- Nanchang University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- First Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-04-08
- DOI
- https://doi.org/10.1007/s12672-025-02288-7
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00