Characterising the role of placental angiotensin-converting enzyme 2 (ACE2) during the onset of oxidative insult by hypoxia/reoxygenation: Implications for fetal growth restriction
We have characterised the redox-sensitive changes that occur in the placenta due to defective placentation and hypoxia/reoxygenation and have shown for the first time the role of placental ACE2 in mitigating oxidative insult associated with hypoxia/reoxygenation.
Authors
- Kirsty G. Pringle (ORCID: https://orcid.org/0000-0002-6770-0496)
- Eugenie R. Lumbers (ORCID: https://orcid.org/0000-0003-3945-3923)
- Joshua J. Fisher (ORCID: https://orcid.org/0000-0002-0505-0598)
- Jessie M. Sutherland (ORCID: https://orcid.org/0000-0001-9672-2371)
- Saije K. Endacott (ORCID: https://orcid.org/0000-0001-8974-5575)
- Sarah J. Delforce (ORCID: https://orcid.org/0000-0003-3109-1518)
- India A Brooker (ORCID: https://orcid.org/0000-0002-0245-9582)
Institutions
- Hunter Medical Research Institute (AU)
- University of Newcastle Australia (AU)
Publication Details
- Journal
- Placenta
- Published
- 2025-04-08
- DOI
- https://doi.org/10.1016/j.placenta.2025.04.008
- Citations
- 3
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 6.17
Funders
- Australian Government
- Australian Research Council