Co-infection in unvaccinated infants with acute pertussis in Western China (2018–2019): pathogen distribution and impact on disease severity

Co-infections are prevalent among unvaccinated infants with acute pertussis in western China. Bacterial and viral pathogens are the most common co-infecting agents, and disease severity increases with the number of co-infecting pathogens. Bacterial co-infections may lead to more severe outcomes compared to viral co-infections, underscoring the need for targeted diagnostic and therapeutic strategies.

Authors

Institutions

Publication Details

Journal
˜The œItalian Journal of Pediatrics/Italian journal of pediatrics
Published
2025-04-09
DOI
https://doi.org/10.1186/s13052-025-01949-1
Citations
4
Primary Topic
Bacterial Infections and Vaccines
Type
article
Field-Weighted Citation Impact
4.73

Funders

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article

Co-infection in unvaccinated infants with acute pertussis in Western China (2018–2019): pathogen distribution and impact on disease severity

Chuan Gan, Yuanyuan Wu
4 citations
˜The œItalian Journal of Pediatrics/Italian journal of pediatrics
Bacterial Infections and Vaccines
4.73
article

Co-infection in unvaccinated infants with acute pertussis in Western China (2018–2019): pathogen distribution and impact on disease severity

Chuan Gan, Yuanyuan Wu
article en
4 citations

Abstract

Co-infections are prevalent among unvaccinated infants with acute pertussis in western China. Bacterial and viral pathogens are the most common co-infecting agents, and disease severity increases with the number of co-infecting pathogens. Bacterial co-infections may lead to more severe outcomes compared to viral co-infections, underscoring the need for targeted diagnostic and therapeutic strategies.

˜The œItalian Journal of Pediatrics/Italian journal of pediatricsVol. 51(1)
Dalian Medical University (CN), Second Affiliated Hospital of Chongqing Medical University (CN), Children's Hospital of Chongqing Medical University (CN), Chongqing Medical University (CN)
National Natural Science Foundation of China, Natural Science Foundation of Chongqing, Centre Scientifique et Technique du Bâtiment
Zero hunger
Openalex Percentile: Top 5%
Bacterial Infections and Vaccines
4.73
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Co-infection in unvaccinated infants with acute pertussis in Western China (2018–2019): pathogen distribution and impact on disease severity — Chuan Gan, Yuanyuan Wu · ˜The œItalian Journal of Pediatrics/Italian journal of pediatrics (2025) | TGRS Research Map | TGRS