A stacked ensemble approach for symptom-based monkeypox diagnosis

The recent monkeypox outbreak has raised global health concerns. Caused by a virus, it is characterized by symptoms such as skin lesions. Early detection is critical for treatment and controlling its spread. This study uses advanced machine learning and deep learning techniques, including Tab Transformer, Long Short-Term Memory, XGBoost, LightGBM, and a Stacking Classifier, to predict the presence of the virus based on patient symptoms. The performance of these models is evaluated using accuracy, precision, recall, and F1-score metrics. The experiments reveal that the Stacking Classifier significantly outperforms the other models, achieving an accuracy of 87.29 %, precision of 86.12 %, recall of 87.47 %, and an F1 score of 87.89 %. Additionally, applying Conditional Tabular GAN to generate synthetic data helps address data imbalance issues, further improving model robustness. These results highlight the proposed approach's potential for timely, accurate monkeypox detection, aiding in effective disease management and control.

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Publication Details

Journal
Computers in Biology and Medicine
Published
2025-04-08
DOI
https://doi.org/10.1016/j.compbiomed.2025.110140
Citations
6
Primary Topic
Poxvirus research and outbreaks
Type
article
Field-Weighted Citation Impact
6.22
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article

A stacked ensemble approach for symptom-based monkeypox diagnosis

Shimaa Abdullah Nagro
6 citations
Computers in Biology and Medicine
Poxvirus research and outbreaks
6.22
article

A stacked ensemble approach for symptom-based monkeypox diagnosis

Shimaa Abdullah Nagro
article en
6 citations

Abstract

The recent monkeypox outbreak has raised global health concerns. Caused by a virus, it is characterized by symptoms such as skin lesions. Early detection is critical for treatment and controlling its spread. This study uses advanced machine learning and deep learning techniques, including Tab Transformer, Long Short-Term Memory, XGBoost, LightGBM, and a Stacking Classifier, to predict the presence of the virus based on patient symptoms. The performance of these models is evaluated using accuracy, precision, recall, and F1-score metrics. The experiments reveal that the Stacking Classifier significantly outperforms the other models, achieving an accuracy of 87.29 %, precision of 86.12 %, recall of 87.47 %, and an F1 score of 87.89 %. Additionally, applying Conditional Tabular GAN to generate synthetic data helps address data imbalance issues, further improving model robustness. These results highlight the proposed approach's potential for timely, accurate monkeypox detection, aiding in effective disease management and control.

Computers in Biology and MedicineVol. 191
Saudi Electronic University (SA)
Openalex Percentile: Top 4%
Poxvirus research and outbreaks
6.22
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A stacked ensemble approach for symptom-based monkeypox diagnosis — Shimaa Abdullah Nagro · Computers in Biology and Medicine (2025) | TGRS Research Map | TGRS