Role of adenosine A3 receptor and endothelial nitric oxide synthase in patients with traumatic hemorrhagic shock
The study emphasizes the importance of ADORA3 and NOS3 gene expressions in influencing shock progression in multiple trauma patients. The increase in ADORA3 gene expression may play a role in restoring vascular reactivity after traumatic shock. Decreased serum NOS3 and ADORA3 levels can contribute to the shock progression in the pathophysiology of multiple trauma.
Authors
- Abdullah Tuncay Demiryürek (ORCID: https://orcid.org/0000-0002-9994-8541)
- Elif Funda Şener (ORCID: https://orcid.org/0000-0002-5644-5442)
- Yusuf Ertuğrul Aslan (ORCID: https://orcid.org/0000-0002-8459-2116)
- Nurullah Günay (ORCID: https://orcid.org/0000-0003-1604-9565)
- Halime Dana (ORCID: https://orcid.org/0000-0003-0829-8625)
- Emre Tuğhan (ORCID: https://orcid.org/0000-0003-1297-9167)
- Yasin Öztaş (ORCID: https://orcid.org/0000-0002-0192-6345)
Institutions
- Gaziantep University (TR)
- Erciyes University (TR)
Publication Details
- Journal
- European Journal of Trauma and Emergency Surgery
- Published
- 2025-04-08
- DOI
- https://doi.org/10.1007/s00068-025-02853-3
- Primary Topic
- Mechanical Circulatory Support Devices
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Erciyes Üniversitesi
- Türkiye Bilimsel ve Teknolojik Araştırma Kurumu