De NAFLD a MAFLD para llegar a MASLD: La nueva nomenclatura de esteatosis hepática metabólica

In 2023, the Delphi method was employed to revise the nomenclature for metabolic steatotic liver disease, resulting in the replacement of the term “metabolic dysfunction associated fatty liver disease (MAFLD)” with “metabolic dysfunction associated steatotic liver disease (MASLD)”. This modification has sparked concerns, criticism, and questions within the scientific community. This review investigates the evolution of terminology over recent decades, with a particular focus on the newly established diagnostic criteria. These criteria are more precise, mitigate the stigmatization associated with the disease, and offer improved alignment with its underlying pathophysiology. As such, this terminological refinement marks a significant advancement in the understanding of steatotic liver disease and presents new challenges for research and therapeutic development.

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Publication Details

Journal
Revista Hospital Clínico Universidad de Chile
Published
2025-04-08
DOI
https://doi.org/10.5354/2735-7996.2025.78118
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
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article

De NAFLD a MAFLD para llegar a MASLD: La nueva nomenclatura de esteatosis hepática metabólica

Deyser Gutiérrez A., Daniela Simian M., Jaime Poniachik T., Martina Contreras M.
Revista Hospital Clínico Universidad de Chile
Liver Disease Diagnosis and Treatment
article

De NAFLD a MAFLD para llegar a MASLD: La nueva nomenclatura de esteatosis hepática metabólica

Deyser Gutiérrez A., Daniela Simian M., Jaime Poniachik T., Martina Contreras M.
article en

Abstract

In 2023, the Delphi method was employed to revise the nomenclature for metabolic steatotic liver disease, resulting in the replacement of the term “metabolic dysfunction associated fatty liver disease (MAFLD)” with “metabolic dysfunction associated steatotic liver disease (MASLD)”. This modification has sparked concerns, criticism, and questions within the scientific community. This review investigates the evolution of terminology over recent decades, with a particular focus on the newly established diagnostic criteria. These criteria are more precise, mitigate the stigmatization associated with the disease, and offer improved alignment with its underlying pathophysiology. As such, this terminological refinement marks a significant advancement in the understanding of steatotic liver disease and presents new challenges for research and therapeutic development.

Revista Hospital Clínico Universidad de ChileVol. 36(1)
Hospital Clínico de la Universidad de Chile (CL)
Openalex Percentile: Top 89%
Liver Disease Diagnosis and Treatment
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