Cellular technologies in the management of patients with post-burn scars of various locations

Aim. To evaluate the effectiveness of different methods of cellular therapy in the postoperative treatment of burn scars of various anatomical locations. Material and methods . The clinical material included 102 patients who underwent surgical procedures for correction of post-burn scars. Depending on the treatment protocol, the surgical procedures were performed with or without concomitant cellular therapy. Results and discussion . Patients treated with a combination of surgery and cellular therapy showed significantly better outcomes, as assessed by the Vancouver Scar Scale and Disability of Arm, Shoulder and Hand (DASH) scores, than those who underwent surgery alone. This improvement was seen in both the primary and repeat subgroups. The combination of surgery and cell therapy reduced the average percentage of disability from baseline by more than half. As expected, the results in the primary subgroup were better than those in the repeat subgroup. Conclusions. Cellular technologies represent a promising component in the integrated management of post-burn scars. The use of platelet-rich plasma (PRP) and autologous adipose tissue in reconstructive and plastic surgery for burn sequelae is safe and effective and significantly reduces the need for repeat surgical interventions.