Effect of GIP and GLP-1 infusion on bone resorption in glucose intolerant, pancreatic insufficient cystic fibrosis
GIP evokes a bone anti-resorptive effect in people with PI-CF. Since the incretin response is perturbed in PI-CF, and an infusion of GIP lowers bone resorption, the "gut-bone axis" in CF-related bone disease requires attention.
Authors
- Joseph M. Kindler (ORCID: https://orcid.org/0000-0001-7613-4548)
- Tanicia Daley (ORCID: https://orcid.org/0000-0002-2736-183X)
- Lingyu Zhao (ORCID: https://orcid.org/0000-0001-9616-2183)
- Xianyan Chen (ORCID: https://orcid.org/0000-0002-1806-0883)
- Bradley Phillips (ORCID: https://orcid.org/0000-0002-2157-9037)
- Wang Shin Lei
- Michael Roehrhoff Rickels (ORCID: https://orcid.org/0000-0002-9253-838X)
- Andrea Kelly (ORCID: https://orcid.org/0000-0003-1724-9868)
Institutions
- Children's Hospital of Philadelphia (US)
- Emory University (US)
- University of Georgia (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Journal of Clinical & Translational Endocrinology
- Published
- 2025-04-08
- DOI
- https://doi.org/10.1016/j.jcte.2025.100392
- Citations
- 1
- Primary Topic
- Pancreatic function and diabetes
- Type
- article
- Field-Weighted Citation Impact
- 2.01