Sorafenib nanocrystals enhance bioavailability and overcome multidrug resistance in liver cancer cells: an approach based on <i>P</i> -gp inhibition strategy
This research aimed to improve the oral bioavailability of Sorafenib (SF) and overcome multidrug resistance in hepatocellular carcinoma cells based on P -glycoprotein ( P -gp) inhibition strategy.
Authors
- Mohamed Nasr (ORCID: https://orcid.org/0000-0001-6382-3221)
- Heba I. Elagamy (ORCID: https://orcid.org/0009-0000-9160-0172)
- Ahmed Gaafar Ahmed Gaafar
- Sameh Saber (ORCID: https://orcid.org/0000-0002-5070-7851)
- Soha M. El-Masry (ORCID: https://orcid.org/0000-0002-3437-2713)
- Shaimaa K. Mostafa (ORCID: https://orcid.org/0000-0002-5866-1114)
- Ahmed A.E. Mourad (ORCID: https://orcid.org/0000-0001-8823-8774)
- Hakeem Asad
Institutions
- Damanhour University (EG)
- Helwan University (EG)
- Port Said University (EG)
- Delta University for Science and Technology (EG)
Publication Details
- Journal
- Materials Advances
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5ma00122f
- Primary Topic
- Drug Transport and Resistance Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00