Insights from comparison of serum IgG4 between T2-eosinophilic asthma and eosinophilic granulomatosis with polyangiitis/idiopathic hypereosinophilic syndrome

Elevated serum IgG4 seemed to discriminate between T2-eosinophilic asthma "alone" and T2-eosinophilic asthma evolved into EGPA/iHES. This finding could represent a reasonable background for prospective long-term studies on asthmatic naive patients aimed at investigating IgG4 as a potential predictive biomarker of progression from asthma to EGPA/iHES.

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Publication Details

Journal
Clinical and Experimental Rheumatology
Published
2025-04-08
DOI
https://doi.org/10.55563/clinexprheumatol/3ihc3t
Primary Topic
Eosinophilic Disorders and Syndromes
Type
article
Field-Weighted Citation Impact
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article

Insights from comparison of serum IgG4 between T2-eosinophilic asthma and eosinophilic granulomatosis with polyangiitis/idiopathic hypereosinophilic syndrome

Maria Beatrice Bilò, Gianluca Moroncini, G Ghirelli, Matteo Martini et al.
Clinical and Experimental Rheumatology
Eosinophilic Disorders and Syndromes
article

Insights from comparison of serum IgG4 between T2-eosinophilic asthma and eosinophilic granulomatosis with polyangiitis/idiopathic hypereosinophilic syndrome

Maria Beatrice Bilò, Gianluca Moroncini, G Ghirelli, Matteo Martini, Angelica Di Vincenzo, Maria Giovanna Danieli, Maria Stella Garritani, Paolo Fraticelli, Leonardo Antonicelli, Giuseppe Pio Martino, Mario Andrea Piga, Maria Chiara Braschi, Alessandro Canalini, Marco Gallifuoco
article en

Abstract

Elevated serum IgG4 seemed to discriminate between T2-eosinophilic asthma "alone" and T2-eosinophilic asthma evolved into EGPA/iHES. This finding could represent a reasonable background for prospective long-term studies on asthmatic naive patients aimed at investigating IgG4 as a potential predictive biomarker of progression from asthma to EGPA/iHES.

Clinical and Experimental RheumatologyVol. 43(4)
Marche Polytechnic University (IT)
Openalex Percentile: Top 89%
Eosinophilic Disorders and Syndromes
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Insights from comparison of serum IgG4 between T2-eosinophilic asthma and eosinophilic granulomatosis with polyangiitis/idiopathic hypereosinophilic syndrome — Maria Beatrice Bilò, Gianluca Moroncini, et al. · Clinical and Experimental Rheumatology (2025) | TGRS Research Map | TGRS