Immunological Parameters for Assessing the In Vitro Safety and Efficacy of Allergoid Mixtures for Immunotherapy

These findings support the use of DPmixE as a promising formulation for allergen immunotherapy, combining stability, reduced enzymatic activity, and enhanced immunological stimulation, while preserving in vitro safety and efficacy comparable to separated depigmented-polymerized extracts.

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Publication Details

Journal
Journal of Investigational Allergology and Clinical Immunology
Published
2025-04-08
DOI
https://doi.org/10.18176/jiaci.1061
Citations
1
Primary Topic
Allergic Rhinitis and Sensitization
Type
article
Field-Weighted Citation Impact
1.62
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Immunological Parameters for Assessing the In Vitro Safety and Efficacy of Allergoid Mixtures for Immunotherapy

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Immunological Parameters for Assessing the In Vitro Safety and Efficacy of Allergoid Mixtures for Immunotherapy

David Calzada, Cristina Galache, J M Beitia, Raquel Moya, David González‐de‐Olano, Jerónimo Carnés, Javier Domínguez‐Ortega, Nuria Parody, Ana Renshaw-Calderón
article en
1 citations

Abstract

These findings support the use of DPmixE as a promising formulation for allergen immunotherapy, combining stability, reduced enzymatic activity, and enhanced immunological stimulation, while preserving in vitro safety and efficacy comparable to separated depigmented-polymerized extracts.

Journal of Investigational Allergology and Clinical ImmunologyVol. 35(6)
Hospital Universitario de Guadalajara (ES), Hospital Universitario Ramón y Cajal (ES)
Good health and well-being
Openalex Percentile: Top 21%
Allergic Rhinitis and Sensitization
1.62
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