Prognostic value of modified shock index in sepsis

Sepsis is a life-threatening condition requiring early diagnosis and severity assessment in the emergency department (ED) to guide timely interventions. Therefore, it is of interest to evaluate the Modified Shock Index (MSI) as a prognostic tool for sepsis and compared its sensitivity and specificity to the quick sequential organ failure assessment (qSOFA) score in 150 sepsis patients, based on Sepsis-3 guidelines. Clinical data, including MSI and qSOFA scores, were collected at admission and patient outcomes were analyzed for mortality and hospital stay duration. An MSI cut-off of 1.28 predicted mortality with high accuracy (AUC 0.946, sensitivity 91.76%, specificity 90.77%), outperforming the qSOFA score (AUC 0.840). MSI is a reliable, easy-to-use bedside tool that surpasses the quick sequential organ failure assessment score in predicting sepsis prognosis, aiding in early identification and management of high-risk patients.

Authors

Institutions

Publication Details

Journal
Bioinformation
Published
2025-04-08
DOI
https://doi.org/10.6026/973206300210614
Citations
1
Primary Topic
Sepsis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
1.35
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Prognostic value of modified shock index in sepsis

Abhinav Meelu, Mini Bhatnagar, Sanchit Uppal, Ena Sharma et al.
1 citations
Bioinformation
Sepsis Diagnosis and Treatment
1.35
article

Prognostic value of modified shock index in sepsis

Abhinav Meelu, Mini Bhatnagar, Sanchit Uppal, Ena Sharma, J. Jacob
article en
1 citations

Abstract

Sepsis is a life-threatening condition requiring early diagnosis and severity assessment in the emergency department (ED) to guide timely interventions. Therefore, it is of interest to evaluate the Modified Shock Index (MSI) as a prognostic tool for sepsis and compared its sensitivity and specificity to the quick sequential organ failure assessment (qSOFA) score in 150 sepsis patients, based on Sepsis-3 guidelines. Clinical data, including MSI and qSOFA scores, were collected at admission and patient outcomes were analyzed for mortality and hospital stay duration. An MSI cut-off of 1.28 predicted mortality with high accuracy (AUC 0.946, sensitivity 91.76%, specificity 90.77%), outperforming the qSOFA score (AUC 0.840). MSI is a reliable, easy-to-use bedside tool that surpasses the quick sequential organ failure assessment score in predicting sepsis prognosis, aiding in early identification and management of high-risk patients.

BioinformationVol. 21(04)
Maharishi Markandeshwar University, Mullana (IN), Rayat Bahra University (IN)
Good health and well-being
Openalex Percentile: Top 21%
Sepsis Diagnosis and Treatment
1.35
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.