Prognostic value of modified shock index in sepsis
Sepsis is a life-threatening condition requiring early diagnosis and severity assessment in the emergency department (ED) to guide timely interventions. Therefore, it is of interest to evaluate the Modified Shock Index (MSI) as a prognostic tool for sepsis and compared its sensitivity and specificity to the quick sequential organ failure assessment (qSOFA) score in 150 sepsis patients, based on Sepsis-3 guidelines. Clinical data, including MSI and qSOFA scores, were collected at admission and patient outcomes were analyzed for mortality and hospital stay duration. An MSI cut-off of 1.28 predicted mortality with high accuracy (AUC 0.946, sensitivity 91.76%, specificity 90.77%), outperforming the qSOFA score (AUC 0.840). MSI is a reliable, easy-to-use bedside tool that surpasses the quick sequential organ failure assessment score in predicting sepsis prognosis, aiding in early identification and management of high-risk patients.
Authors
- Abhinav Meelu (ORCID: https://orcid.org/0000-0002-2848-8007)
- Mini Bhatnagar (ORCID: https://orcid.org/0000-0002-2354-3935)
- Sanchit Uppal
- Ena Sharma
- J. Jacob
Institutions
- Maharishi Markandeshwar University, Mullana (IN)
- Rayat Bahra University (IN)
Publication Details
- Journal
- Bioinformation
- Published
- 2025-04-08
- DOI
- https://doi.org/10.6026/973206300210614
- Citations
- 1
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.35