Whole Exome Sequencing Study Identifies Distinct Characteristics of Transformed Small Cell Lung Cancer With <scp>EGFR</scp> Mutation Compared to De Novo Small Cell and Primary Non‐Small Cell Lung Cancers
The identification of these specific genomic alterations in transformed SCLC contributes to a better understanding of the mechanisms driving this transformation. This knowledge may guide future predicting the transformation of SCLC and the development of personalized treatment strategies for these patients.
Authors
- Dan Zhao (ORCID: https://orcid.org/0000-0002-1593-598X)
- Nanying Che (ORCID: https://orcid.org/0000-0001-7890-8957)
- Jinjing Tan (ORCID: https://orcid.org/0000-0003-3534-8376)
- Jie Li (ORCID: https://orcid.org/0000-0001-9359-3586)
- Yanjing Peng
- Ying Hu (ORCID: https://orcid.org/0000-0003-0301-7273)
- Xi Li (ORCID: https://orcid.org/0000-0002-9601-5076)
- Qunhui Wang (ORCID: https://orcid.org/0000-0002-8102-0622)
- Hua Zheng (ORCID: https://orcid.org/0000-0002-3053-4113)
Institutions
- Capital Medical University (CN)
- Beijing Chest Hospital (CN)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1002/cam4.70838
- Citations
- 3
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 4.56