KRASG12D Cells Override Homeostatic Cell Elimination Mechanisms in Adult Pancreas Via Wnt5a and Cell Dormancy
RAS mutant cells activate Wnt5a and cell dormancy to avoid cell expulsion and to survive in the adult pancreas.
Authors
- Jennifer P. Morton (ORCID: https://orcid.org/0000-0001-5766-9141)
- Markella Alatsatianos
- Owen J. Sansom (ORCID: https://orcid.org/0000-0001-9540-3010)
- Catherine Hogan (ORCID: https://orcid.org/0000-0002-1012-0896)
- Beatriz Salvador-Barberó (ORCID: https://orcid.org/0000-0003-3842-2383)
Institutions
- University of Glasgow (GB)
- Cardiff University (GB)
- Cardiff Metropolitan University (GB)
Publication Details
- Journal
- Gastroenterology
- Published
- 2025-04-08
- DOI
- https://doi.org/10.1053/j.gastro.2025.02.042
- Citations
- 6
- Primary Topic
- Pancreatic function and diabetes
- Type
- article
- Field-Weighted Citation Impact
- 12.04
Funders
- Pancreatic Cancer UK
- Cancer Research UK