Plasma Epstein-Barr Virus DNA Temporal Clearance Pattern During Induction-Concurrent (Chemo)Radiation Therapy for Risk Stratification in Nasopharyngeal Carcinoma
Temporal EBV DNA clearance patterns during induction-concurrent chemoRT provide valuable prognostic insights, enabling the identification of patients with high-risk NPC and informing personalized treatment strategies. Resurgence of EBV DNA may occur occasionally (3.3%). Caution is required when considering reduced-intensity therapy in patients with locoeregionally advanced disease when EBV DNA becomes U after induction chemotherapy.
Authors
- Lishui Wu
- Jun Lü (ORCID: https://orcid.org/0000-0002-9141-6786)
- Sufang Qiu (ORCID: https://orcid.org/0000-0001-7660-6955)
- Ying Li (ORCID: https://orcid.org/0000-0001-5062-0230)
- Yi Li (ORCID: https://orcid.org/0000-0001-7994-5362)
- Zihan Chen (ORCID: https://orcid.org/0009-0006-3412-0897)
- Wenxi Wu
- Jinghua Lai (ORCID: https://orcid.org/0009-0005-4528-7564)
- Siqi Xu (ORCID: https://orcid.org/0000-0002-8958-1889)
- Zongwei Huang (ORCID: https://orcid.org/0000-0003-0981-2999)
Institutions
- Fujian Medical University (CN)
- Fujian Provincial Cancer Hospital (CN)
Publication Details
- Journal
- International Journal of Radiation Oncology*Biology*Physics
- Published
- 2025-04-08
- DOI
- https://doi.org/10.1016/j.ijrobp.2025.03.076
- Citations
- 8
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 14.78