Effects of Multiple Intravenous Doses of Perioperative Vitamin C on Pain Management Following Total Hip Arthroplasty

In the vitamin C group, the subcutaneous morphine injection dosage was considerably lower (0-24h 6.1mg ± 2.7mg vs 4.0mg ± 2.9mg, p = 0.000, total use 8.3mg ± 3.1mg vs 6.6mg ± 3.9mg, p = 0.018). During the perioperative term, the vitamin C group experienced better hip motion and lower VAS pain levels at rest and during exercise.

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Publication Details

Journal
Drug Design Development and Therapy
Published
2025-04-01
DOI
https://doi.org/10.2147/dddt.s506262
Primary Topic
Vitamin C and Antioxidants Research
Type
article
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0.00
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article

Effects of Multiple Intravenous Doses of Perioperative Vitamin C on Pain Management Following Total Hip Arthroplasty

Yuna Ye, Pengde Kang, Guangtao Han
Drug Design Development and Therapy
Vitamin C and Antioxidants Research
article

Effects of Multiple Intravenous Doses of Perioperative Vitamin C on Pain Management Following Total Hip Arthroplasty

Yuna Ye, Pengde Kang, Guangtao Han
article en

Abstract

In the vitamin C group, the subcutaneous morphine injection dosage was considerably lower (0-24h 6.1mg ± 2.7mg vs 4.0mg ± 2.9mg, p = 0.000, total use 8.3mg ± 3.1mg vs 6.6mg ± 3.9mg, p = 0.018). During the perioperative term, the vitamin C group experienced better hip motion and lower VAS pain levels at rest and during exercise.

Drug Design Development and TherapyVol. Volume 19
Sichuan University (CN), West China Hospital of Sichuan University (CN), Northwest Institute of Mining and Metallurgy (CN)
Zero hunger
Openalex Percentile: Top 92%
Vitamin C and Antioxidants Research
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