Electroorganocatalytic asymmetric Diels–Alder cycloaddition of hydroquinones with α,β-unsaturated aldehydes
The concept of combining asymmetric aminocatalysis with electrochemistry remains underexplored. Herein, we report an electrochemically driven Diels-Alder cycloaddition reaction of substituted hydroquinones with a series of enals activated by a TMS-protected prolinol catalyst, leading to optically active products with high yields and perfect enantiomeric ratios up to 99 : 1 e.r.
Authors
- Dominika Pomikło (ORCID: https://orcid.org/0000-0003-1297-8922)
- Anna Albrecht (ORCID: https://orcid.org/0000-0001-9948-3986)
- Lesław Sieroń (ORCID: https://orcid.org/0000-0002-7797-0262)
- Krzysztof Romaniuk
Institutions
- Lodz University of Technology (PL)
- Institute of Organic Chemistry (PL)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc00505a
- Citations
- 4
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 3.74
Funders
- Narodowym Centrum Nauki