Enhancement of Platinum-Based Drug Sensitivity in Ovarian Cancer Cells Through Hyperthermia-Induced Activation of the TGF-β1/β-Catenin Signaling Pathway

Hyperthermia boosts the effectiveness of platinum-based drugs in ovarian cancer by suppressing the TGF-β1/β-catenin pathway, presenting a potential strategy to overcome chemoresistance and improve patient outcomes.

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Publication Details

Journal
Current Molecular Medicine
Published
2025-04-07
DOI
https://doi.org/10.2174/0115665240367566250327040010
Primary Topic
Renal and related cancers
Type
article
Field-Weighted Citation Impact
0.00
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article

Enhancement of Platinum-Based Drug Sensitivity in Ovarian Cancer Cells Through Hyperthermia-Induced Activation of the TGF-β1/β-Catenin Signaling Pathway

Song Zeng, Xiaogang Lv, Xiaowen Yao, Gaoting Huang et al.
Current Molecular Medicine
Renal and related cancers
article

Enhancement of Platinum-Based Drug Sensitivity in Ovarian Cancer Cells Through Hyperthermia-Induced Activation of the TGF-β1/β-Catenin Signaling Pathway

Song Zeng, Xiaogang Lv, Xiaowen Yao, Gaoting Huang, Wenjuan Wu, Yifeng Wang
article en

Abstract

Hyperthermia boosts the effectiveness of platinum-based drugs in ovarian cancer by suppressing the TGF-β1/β-catenin pathway, presenting a potential strategy to overcome chemoresistance and improve patient outcomes.

Current Molecular MedicineVol. 25
Sun Yat-sen University (CN), Zhujiang Hospital (CN), Guangzhou Medical University Cancer Hospital (CN), Southern Medical University (CN), Guangzhou Medical University (CN)
Good health and well-being
Openalex Percentile: Top 94%
Renal and related cancers
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