The Potential Influence of Associated Antidepressants on the Pharmacokinetic Profile of Esketamine in Patients Affected by Treatment-resistant Depression
The CY<sub>450</sub>-related status of co-administered antidepressants may affect esketamine levels. However, the small sample sizes of the co-administered drug subgroups and multiple prescriptions do not allow for drawing strong conclusions.
Authors
- Alessia Ceccherelli (ORCID: https://orcid.org/0000-0003-1461-0814)
- Donatella De Bernardini
- Sergio De Filippis (ORCID: https://orcid.org/0000-0002-6521-3379)
- Maurizio Simmaco (ORCID: https://orcid.org/0000-0003-4164-1472)
- Luana Lionetto (ORCID: https://orcid.org/0000-0002-5272-6642)
- D. Donato
- Edoardo Bianchini (ORCID: https://orcid.org/0000-0001-7955-3369)
- Luca Montaguti
- Giuseppe Costanzi
- Georgios D. Kotzalidis (ORCID: https://orcid.org/0000-0002-0281-6324)
- Ilaria Pagano
- Marika Alborghetti (ORCID: https://orcid.org/0000-0001-9327-6660)
- Giovanni Martinotti (ORCID: https://orcid.org/0000-0002-7292-2341)
- Giorgio Di Lorenzo (ORCID: https://orcid.org/0000-0002-0576-4064)
- Federica Catapano (ORCID: https://orcid.org/0000-0002-1004-5451)
- Giada Trovini (ORCID: https://orcid.org/0000-0001-8711-5326)
- Ginevra Lombardozzi (ORCID: https://orcid.org/0009-0002-7039-1820)
- Michele Surano
- Ferdinando Nicoletti (ORCID: https://orcid.org/0000-0003-3366-7269)
Institutions
- University of Rome Tor Vergata (IT)
- University of Hertfordshire (GB)
- Istituto Neurologico Mediterraneo (IT)
- University of Chieti-Pescara (IT)
- Fondazione Santa Lucia (IT)
- Villa Torri Hospital (IT)
- Sapienza University of Rome (IT)
- Université Grenoble Alpes (FR)
Publication Details
- Journal
- Current Neuropharmacology
- Published
- 2025-04-08
- DOI
- https://doi.org/10.2174/011570159x356952241216172603
- Citations
- 1
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 1.39