Age-Dependent Correlation between Immune Parameters and Symptoms in Young Adults with Schizophrenia

Our study suggests that young adult patients had abnormal immune parameters. Furthermore, age mediated the relationships between immune parameters and symptom severity. This study provides further evidence that abnormal immune parameters, particularly an increased innate immune response, may be involved in the pathophysiology of SCZ.

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Publication Details

Journal
Current Neuropharmacology
Published
2025-04-08
DOI
https://doi.org/10.2174/1570159x23666250407092539
Primary Topic
Tryptophan and brain disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Age-Dependent Correlation between Immune Parameters and Symptoms in Young Adults with Schizophrenia

Yuanyuan Huang, Meihong Xiu, Xiaoni Guan, Cheng Zhu et al.
Current Neuropharmacology
Tryptophan and brain disorders
article

Age-Dependent Correlation between Immune Parameters and Symptoms in Young Adults with Schizophrenia

Yuanyuan Huang, Meihong Xiu, Xiaoni Guan, Cheng Zhu, Nan Chen
article en

Abstract

Our study suggests that young adult patients had abnormal immune parameters. Furthermore, age mediated the relationships between immune parameters and symptom severity. This study provides further evidence that abnormal immune parameters, particularly an increased innate immune response, may be involved in the pathophysiology of SCZ.

Current NeuropharmacologyVol. 23(10)
Peking University (CN), Wenzhou Medical University (CN), Center for Translational Molecular Medicine (NL), Jinzhou Kangning Hospital (CN), Beijing HuiLongGuan Hospital (CN), Guangzhou Medical University (CN)
National Natural Science Foundation of China, Basic and Applied Basic Research Foundation of Guangdong Province
Good health and well-being
Openalex Percentile: Top 94%
Tryptophan and brain disorders
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Age-Dependent Correlation between Immune Parameters and Symptoms in Young Adults with Schizophrenia — Yuanyuan Huang, Meihong Xiu, et al. · Current Neuropharmacology (2025) | TGRS Research Map | TGRS